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25种分析物在人血清中于22摄氏度、4摄氏度和零下20摄氏度时的稳定性

Stability of twenty-five analytes in human serum at 22 degrees C, 4 degrees C, and -20 degrees C.

作者信息

Donnelly J G, Soldin S J, Nealon D A, Hicks J M

机构信息

Institute for Biomolecular Studies, Cathologic University of America, Washington, DC, USA.

出版信息

Pediatr Pathol Lab Med. 1995 Nov-Dec;15(6):869-74. doi: 10.3109/15513819509027023.

DOI:10.3109/15513819509027023
PMID:8705197
Abstract

The stability of 25 analytes from serum of healthy donors was determined at room temperature, 4 degrees C, and -20 degrees C over 48 h, 14 days, and 4 months, respectively. Glucose, blood urea nitrogen, sodium, potassium, chloride, creatinine, calcium, phosphorus, uric acid, total protein, albumin, triglycerides, lipase, total creatine kinase, gamma-glutamyltransferase, iron, magnesium, and cholesterol were stable at all three temperatures for the specified times. Carbon dioxide, aspartate and alanine aminotransferases, lactate dehydrogenase, amylase, alkaline phosphatase, and high-density lipoprotein cholesterol demonstrated some loss over time. Proper storage temperatures and times must be considered for these analytes if measurement is not to take place immediately after specimen collection.

摘要

分别在室温、4℃和-20℃下测定了健康供体血清中25种分析物在48小时、14天和4个月内的稳定性。葡萄糖、血尿素氮、钠、钾、氯、肌酐、钙、磷、尿酸、总蛋白、白蛋白、甘油三酯、脂肪酶、总肌酸激酶、γ-谷氨酰转移酶、铁、镁和胆固醇在所有三种温度下在规定时间内均保持稳定。二氧化碳、天冬氨酸和丙氨酸转氨酶、乳酸脱氢酶、淀粉酶、碱性磷酸酶和高密度脂蛋白胆固醇随时间有一定损失。如果在标本采集后不立即进行测量,则必须考虑这些分析物的合适储存温度和时间。

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