Ndip R N, Obi C L, Agbonlahor D E, Igumbor E O, Ayamba L M
Department of Life Sciences, Faculty of Science, University of Buea, Cameroon.
J Diarrhoeal Dis Res. 1996 Mar;14(1):41-3.
One hundred patients with diarrhoea and 50 asymptomatic individuals attending various hospitals in Edo State, Nigeria, were screened for serum complement-fixing and agglutinating antibodies to Plesiomonas shigelloides using the complement-fixation and agglutination tests. Seventy (70%) of the 100 patients and 20 (40%) of the 50 asymptomatic individuals had detectable complement-fixing antibodies at titres ranging from 1:32 to 1:128 and 1:8 to 1:32 respectively. Results suggest that cases of diarrhoea in this environment may be due to P. shigelloides, but the demonstration of antibodies in asymptomatic individuals show that they also have serum antibodies against P. shigelloides. The exclusive use of antibody responses in the diagnosis of P. shigelloides infections should, therefore, be interpreted with caution.
在尼日利亚江户州的多家医院，对100名腹泻患者和50名无症状个体进行了筛查，采用补体结合试验和凝集试验检测他们血清中针对类志贺邻单胞菌的补体结合抗体和凝集抗体。100名患者中有70名（70%）、50名无症状个体中有20名（40%）可检测到补体结合抗体，其滴度分别为1:32至1:128和1:8至1:32。结果表明，在这种环境下的腹泻病例可能是由类志贺邻单胞菌引起的，但无症状个体中抗体的检测表明他们也有针对类志贺邻单胞菌的血清抗体。因此，在类志贺邻单胞菌感染诊断中单纯使用抗体反应时应谨慎解读。
