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一例因胰岛素瘤导致低血糖引发阵发性肌张力障碍性舞蹈手足徐动症的病例报告。

A case report of paroxysmal dystonic choreoathetosis due to hypoglycaemia induced by an insulinoma.

作者信息

Shaw C, Haas L, Miller D, Delahunt J

机构信息

Neurology Department, King's College School of Medicine and Dentistry, London, UK.

出版信息

J Neurol Neurosurg Psychiatry. 1996 Aug;61(2):194-5. doi: 10.1136/jnnp.61.2.194.

Abstract

Hypoglycaemia due to an insulinoma can mimic acute disorders of cognition, consciousness, epilepsy, transient ischaemia, or psychosis, and chronic disorders of dementia and neuropathy. Misdiagnosis and delay in treatment are common and prolonged hypoglycaemia can lead to permanent neurological deficit or fatal coma. A 27 year old woman with hypoglycaemia induced by an insulinoma presented with features typical of paroxysmal non-kinesiogenic dystonic choreoathetosis. Striatal dysfunction as a consequence of hypoglycaemia has rarely been described. Insulinoma is a readily treatable condition that should be considered in the differential diagnosis of a paroxysmal movement disorder.

摘要

胰岛素瘤所致低血糖可酷似急性认知障碍、意识障碍、癫痫、短暂性脑缺血发作或精神病,以及慢性痴呆和神经病变。误诊和治疗延误很常见,而长期低血糖可导致永久性神经功能缺损或致命性昏迷。一名27岁因胰岛素瘤诱发低血糖的女性,表现出阵发性非运动诱发性肌张力障碍性舞蹈手足徐动症的典型特征。低血糖导致纹状体功能障碍的情况鲜有报道。胰岛素瘤是一种易于治疗的疾病,在阵发性运动障碍的鉴别诊断中应予以考虑。

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本文引用的文献

3
Paroxysmal choreoathetosis due to hypoglycemia.低血糖所致的阵发性舞蹈手足徐动症。
Arch Neurol. 1984 Mar;41(3):341-2. doi: 10.1001/archneur.1984.04050150123033.
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A prospective survey for insulinomas in a neurology department.神经内科胰岛素瘤前瞻性调查。
Lancet. 1983 May 14;1(8333):1094-5. doi: 10.1016/s0140-6736(83)91923-2.
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Neurological aspects of insulinomas.胰岛素瘤的神经学方面
Postgrad Med J. 1984 Sep;60(707):577-81. doi: 10.1136/pgmj.60.707.577.
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Hypoglycemic peripheral neuropathy.低血糖性周围神经病
Arch Neurol. 1969 Aug;21(2):121-32. doi: 10.1001/archneur.1969.00480140021002.

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