Shaw C, Haas L, Miller D, Delahunt J
Neurology Department, King's College School of Medicine and Dentistry, London, UK.
J Neurol Neurosurg Psychiatry. 1996 Aug;61(2):194-5. doi: 10.1136/jnnp.61.2.194.
Hypoglycaemia due to an insulinoma can mimic acute disorders of cognition, consciousness, epilepsy, transient ischaemia, or psychosis, and chronic disorders of dementia and neuropathy. Misdiagnosis and delay in treatment are common and prolonged hypoglycaemia can lead to permanent neurological deficit or fatal coma. A 27 year old woman with hypoglycaemia induced by an insulinoma presented with features typical of paroxysmal non-kinesiogenic dystonic choreoathetosis. Striatal dysfunction as a consequence of hypoglycaemia has rarely been described. Insulinoma is a readily treatable condition that should be considered in the differential diagnosis of a paroxysmal movement disorder.
胰岛素瘤所致低血糖可酷似急性认知障碍、意识障碍、癫痫、短暂性脑缺血发作或精神病,以及慢性痴呆和神经病变。误诊和治疗延误很常见,而长期低血糖可导致永久性神经功能缺损或致命性昏迷。一名27岁因胰岛素瘤诱发低血糖的女性,表现出阵发性非运动诱发性肌张力障碍性舞蹈手足徐动症的典型特征。低血糖导致纹状体功能障碍的情况鲜有报道。胰岛素瘤是一种易于治疗的疾病,在阵发性运动障碍的鉴别诊断中应予以考虑。