Gupta Meena, Batra Amit, Hirve Makarand, Chowdhury Debashish, Khwaja Geeta A, Mishra P K
Department of Neurology, GB Pant Hospital, JLN Marg, New Delhi, India.
Ann Indian Acad Neurol. 2011 Oct;14(4):313-5. doi: 10.4103/0972-2327.91965.
Neurological syndromes are not an uncommon presentation with insulinomas. Recurrent hypoglycemia associated with it can present with a variety of neurological symptoms that may include disturbances of consciousness, seizures, stroke-like presentation, movement disorder, dementia and chronic neuropathy. The myriad of presentations, resemblance with other neurological conditions and episodic nature often lead to misdiagnosis and a delay in definitive treatment. Rare cases of insulinoma presenting as combination of abnormal movements have been described. We report a patient who presented with both hypoglycemia induced symptomatic seizures and paroxysmal non-kinesiogenic dystonic choreoathetosis. Insulinoma is a potentially treatable disorder and early definitive intervention can prevent long term neurological disability in patients.
神经综合征在胰岛素瘤患者中并非不常见的表现。与之相关的反复低血糖可出现多种神经症状，可能包括意识障碍、癫痫发作、类似中风的表现、运动障碍、痴呆和慢性神经病变。其众多的表现形式、与其他神经疾病的相似性以及发作性特点常常导致误诊和确定性治疗的延迟。已有胰岛素瘤表现为异常运动组合的罕见病例报道。我们报告1例同时出现低血糖诱发的症状性癫痫发作和阵发性非运动诱发性肌张力障碍性舞蹈手足徐动症的患者。胰岛素瘤是一种潜在可治疗的疾病，早期确定性干预可预防患者出现长期神经功能残疾。
