Goldman S, Amrom D, Szliwowski H B, Detemmerman D, Goldman S, Bidaut L M, Stanus E, Luxen A
PET/Biomedical Cyclotron Unit, Université Libre de Bruxelles-Hôpital Erasme, Belgium.
Mov Disord. 1993 Jul;8(3):355-8. doi: 10.1002/mds.870080318.
We studied a 10-year-old girl with Sydenham's chorea (SC) using positron emission tomography (PET) with fluorodeoxyglucose (FDG). Choreic movements involved the head and the left side of her body. PET showed increased glucose metabolism in the right caudate nucleus and putamen. Three months after complete recovery, striatal glucose metabolism had returned to normal in the caudate nucleus. In the right putamen, glucose metabolism had decreased compared to that in the first study but remained elevated compared to that of normal young adults. We propose that the transient striatal hypermetabolism may have been due to increased afferent inputs to the striatum as a consequence of striatal or subthalamic nucleus dysfunction.
我们使用氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）对一名患有 Sydenham 舞蹈病（SC）的 10 岁女孩进行了研究。舞蹈样动作累及头部和身体左侧。PET 显示右侧尾状核和壳核葡萄糖代谢增加。完全恢复三个月后，尾状核的纹状体葡萄糖代谢已恢复正常。在右侧壳核，与首次研究相比，葡萄糖代谢有所下降，但与正常年轻成年人相比仍处于升高状态。我们提出，短暂的纹状体代谢亢进可能是由于纹状体或丘脑底核功能障碍导致纹状体传入输入增加所致。
