Cook G J, Ryan P J, Clarke S E, Fogelman I
Department of Nuclear Medicine, Guys Hospital, London, United Kingdom.
J Nucl Med. 1996 Aug;37(8):1353-6.
This retrospective analysis of SPECT bone scans of the knee was undertaken to define typical bone scan appearances and to assess the sensitivity of this method. We looked at 14 patients, mostly with chronic knee pain, who had anterior cruciate ligament (ACL) tears detected by MRI.
Of the 14 patients, 10 were referred for bone scanning following injury and 4 complained of chronic knee pain without injury. Planar scans were performed 4 hr after the injection of 750 MBq of 99mTc-MDP. Tomographic images were obtained by a 64 x 20-sec acquisition over 360 degrees using a high-resolution collimator. MRI imaging included axial and sagittal, T1 weighted and coronal fast field echo (FFE) sequences. Ten patients also had arthroscopy performed.
MRI scans showed 6 lone ACL tears and 8 combined with other ligamentous injuries. SPECT scans showed abnormalities in 10 patients in the region of ACL insertions but only 4 planar studies were abnormal. SPECT identified focal activity at the upper (n = 8) or lower (n = 2) insertion of the ACL. Six of 10 arthroscopies confirmed ACL tears, 2 complete and 4 partial. Overall, agreement was found with MRI in 10 of 14 cases and in 8 of 10 with arthroscopy. Abnormalities were identified in 10 of 11 regions of other ligament or bone injury identified by MRI.
SPECT bone scanning of the knee is superior to planar imaging in detecting ACL injury and is a sensitive technique. Focal activity may be seen at either end of ACL attachment but more commonly at the upper femoral insertion. Knee SPECT may be a valuable examination in suspected ACL injury, particularly if MRI is not available, is equivocal or where clinical signs are absent.
对膝关节SPECT骨扫描进行了这项回顾性分析,以确定典型的骨扫描表现并评估该方法的敏感性。我们观察了14例患者,大多数有慢性膝关节疼痛,他们通过MRI检测出前交叉韧带(ACL)撕裂。
14例患者中,10例在受伤后被转诊进行骨扫描,4例主诉无受伤史的慢性膝关节疼痛。在注射750MBq的99mTc-MDP后4小时进行平面扫描。使用高分辨率准直器通过360度64×20秒采集获得断层图像。MRI成像包括轴向和矢状面、T1加权和冠状面快速场回波(FFE)序列。10例患者还进行了关节镜检查。
MRI扫描显示6例单纯ACL撕裂和8例合并其他韧带损伤。SPECT扫描显示10例患者在ACL附着区域有异常,但只有4例平面研究异常。SPECT在ACL上(n = 8)或下(n = 2)附着处发现局灶性活动。10例关节镜检查中有6例证实ACL撕裂,2例完全撕裂,4例部分撕裂。总体而言,14例中有10例与MRI结果一致,10例中有8例与关节镜检查结果一致。在MRI确定的其他韧带或骨损伤的11个区域中有10个发现异常。
膝关节SPECT骨扫描在检测ACL损伤方面优于平面成像,是一种敏感的技术。在ACL附着的两端均可看到局灶性活动,但更常见于股骨上端附着处。膝关节SPECT对于疑似ACL损伤可能是一项有价值的检查,特别是在没有MRI、MRI结果不明确或缺乏临床体征的情况下。