Lin M S
Radiology. 1977 Jun;123(3):783-6. doi: 10.1148/123.3.783.
The first 111In chelate exhibiting hepatobiliary excretion, a 111In-phenolphthalexon, has been formulated and tested in rats. The preparation of the chelate is simple, reflecting its inherently high stability. Its capability for extended cholescintigraphy allowed distinct visualization of the gallbladder and the bowel to the level of the rectosigmoid in dogs. No lethality or acute toxicity was induced by administration of the chelate.
首个表现出肝胆排泄功能的铟-111螯合物，即铟-111酚酞络合物，已在大鼠体内配制并进行了测试。该螯合物的制备方法简单，这反映出其本身具有很高的稳定性。其用于延长胆管闪烁显像的能力使得在犬类动物中能清晰观察到胆囊以及直至直肠乙状结肠部位的肠道。给予该螯合物未引发致死性或急性毒性反应。
