Lin M S, Kam J I, Goodwin D A, Kriss J P
Invest Radiol. 1978 Jul-Aug;13(4):356-9. doi: 10.1097/00004424-197807000-00015.
111In has been complexed to a series of metal-complexing phthaleins and sulfonphthaleins, and the hepatobiliary excretion of the compounds were compared in rats. The highest biliary excretion was obtained with 111In-o-cresolphthalexon. In a normal human subject, sequential imaging with 111In-o-cresolphthalexon visualized his gallbladder, common bile duct, and the bowel from jejunum to rectum. The potential utility and limitation of this biliary scanning agent is discussed.
铟-111已与一系列金属络合酞菁和磺酞菁形成络合物，并在大鼠中比较了这些化合物的肝胆排泄情况。使用铟-111邻甲酚酞络合剂获得了最高的胆汁排泄率。在一名正常人类受试者中，用铟-111邻甲酚酞络合剂进行的序贯成像显示了他的胆囊、胆总管以及从空肠到直肠的肠道。本文讨论了这种胆汁扫描剂的潜在用途和局限性。
