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致敏淋巴细胞对结核菌素超敏反应的系列体外转移

Serial in vitro transfer of tuberculin hypersensitivity by sensitised lymphocytes.

作者信息

Fazio M, Carnevale-Schianca F, Sabidussi A

机构信息

Chair of Medical Onclogy, University of Turin, Italy.

出版信息

Panminerva Med. 1995 Dec;37(4):182-5.

PMID:8710397
Abstract

An account is given of the experimental serial in vitro transfer of PPD-specific delayed hypersensitivity to peripheral leukocytes using PPD-specific TF solely as the initial source. Transfer was assessed by means of the leukocytes migration inhibition test, the lymphocytes locomotion test and the leukocytes adherence inhibition test. These tests were positive in all the experiments. It is suggested that these results indicates that TF does not act in itself but triggers a reaction that expands the effect of hypersensitivity.

摘要

本文介绍了仅以PPD特异性转移因子(TF)作为初始来源,将PPD特异性迟发型超敏反应体外连续实验性转移至外周血白细胞的情况。通过白细胞迁移抑制试验、淋巴细胞移动试验和白细胞黏附抑制试验评估转移情况。所有实验中这些试验均呈阳性。提示这些结果表明TF本身不起作用,而是引发一种反应,扩大超敏反应的效应。

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