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致敏淋巴细胞在体内传递结核菌素超敏反应。

Transfer in vivo of tuberculin hypersensitivity by sensitised lymphocytes.

作者信息

Fazio M, Calabrese F, Giacomasso S, Meina G, Negri L, Mastromatteo V

机构信息

Chair of Medical Oncology, University of Turin, Italy.

出版信息

Panminerva Med. 1993 Sep;35(3):149-53.

PMID:8090529
Abstract

An account is given of the experimental in vivo transfer of PPD-specific delayed hypersensitivity with a very small number of autologous lymphocytes pre-sensitised with PPD-specific transfer factor (TF). Transfer was assessed in 17 volunteers both in vivo by means of the Mantoux skin reaction, and in vitro by means of the leukocyte migration inhibition test, the lymphocyte locomotion test, and the leukocyte adherence inhibition test. Positivization of the tests suggests that TF triggers a reaction which expands the effect of hypersensitivity.

摘要

本文介绍了用极少量经PPD特异性转移因子(TF)预致敏的自体淋巴细胞进行PPD特异性迟发型超敏反应的体内实验性转移。通过17名志愿者进行评估,体内评估采用结核菌素皮肤反应,体外评估采用白细胞迁移抑制试验、淋巴细胞移动试验和白细胞黏附抑制试验。试验呈阳性表明TF引发了一种反应,这种反应扩大了超敏反应的效果。

相似文献

1
Transfer in vivo of tuberculin hypersensitivity by sensitised lymphocytes.致敏淋巴细胞在体内传递结核菌素超敏反应。
Panminerva Med. 1993 Sep;35(3):149-53.
2
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