Fazio M, Calabrese F, Giacomasso S, Negri L, Mastromatteo V
Chair of Medical Oncology, University of Turin, Italy.
Panminerva Med. 1993 Jun;35(2):96-100.
An account is given of the experimental in vitro transfer of PPD-specific delayed hypersensitivity to peripheral leukocytes pulsed with a very small portion of autologous lymphocytes pre-sensitised with PPD-specific transfer factor (TF). Transfer was assessed by means of the leukocyte migration inhibition test, the lymphocyte locomotion test, and the leukocyte adherence inhibition test. These tests were positivized in all the experiments. It is suggested that these results indicate that TF does not act in itself, but triggers a reaction that expands the effect of hypersensitivity.
本文报道了将PPD特异性迟发型超敏反应体外实验性转移至外周血白细胞的过程，这些白细胞用极少量经PPD特异性转移因子（TF）预致敏的自体淋巴细胞进行脉冲处理。通过白细胞迁移抑制试验、淋巴细胞运动试验和白细胞黏附抑制试验评估转移情况。在所有实验中这些试验均呈阳性。提示这些结果表明TF本身并不起作用，而是引发一种反应，扩大超敏反应的效应。
