Flegr J, Zitková S, Kodym P, Frynta D
Department of Parasitology, Charles University, Prague, Czech Republic.
Parasitology. 1996 Jul;113 ( Pt 1):49-54. doi: 10.1017/s0031182000066269.
Toxoplasma gondii, the coccidian parasite, is known to induce changes in the behaviour of its intermediate hosts. The high prevalence of this parasite in the human population (20-80%) offers the opportunity of studying the influence of the parasite on human behaviour by screening of a normal population. A total of 224 men and 170 women were tested for toxoplasmosis and their personality profiles were measured by Cattell's questionnaire. Highly significant differences between Toxoplasma-infected and uninfected subjects were observed (P < 0.01). For men the factors G (low superego strength), L (protension), O (guilt proneness), and Q2 (group dependency) were positively influenced in infected subjects. For women the prevailing factors were A (affectothymia, P < 0.01), L (alaxia), O (untroubled adequacy) and Q2 (self-sufficiency). To reveal whether toxoplasmosis induces personality factor-shifts or whether certain combinations of personality factors influence the probability of acquiring Toxoplasma infection, we examined the personality profiles of 164 male patients diagnosed with acute toxoplasmosis during the past 13 years. The existence of a positive correlation between the duration of latent toxoplasmosis and the intensity of superego strength decrease (P < 0.02) suggested that the decrease of superego strength (the willingness to accept group moral standards) was induced by T. gondii infection.
球虫寄生虫刚地弓形虫已知会引起其中间宿主行为的变化。这种寄生虫在人群中的高感染率（20%-80%）为通过对正常人群进行筛查来研究寄生虫对人类行为的影响提供了机会。共有224名男性和170名女性接受了弓形虫病检测，并通过卡特尔问卷测量了他们的性格特征。在弓形虫感染和未感染的受试者之间观察到了高度显著的差异（P<0.01）。对于男性，感染受试者的因素G（低超我强度）、L（紧张性）、O（内疚倾向）和Q2（群体依赖性）受到了积极影响。对于女性，主要因素是A（情感稳定性，P<0.01）、L（松弛性）、O（无忧无虑的充足感）和Q2（自给自足）。为了揭示弓形虫病是否会导致人格因素的转变，或者某些人格因素的组合是否会影响感染弓形虫的概率，我们检查了过去13年中被诊断为急性弓形虫病的164名男性患者的人格特征。潜伏性弓形虫病持续时间与超我强度降低强度之间存在正相关（P<0.02），这表明超我强度的降低（接受群体道德标准的意愿）是由刚地弓形虫感染引起的。
