Bartone F F, Gardner P J, Hutson J C
Urology. 1977 May;9(5):521-5. doi: 10.1016/0090-4295(77)90244-8.
Cystotomies in guinea pigs and ureteral anastomoses in dogs were sutured with polyglactin 910. Silk and chromic catgut were used as control sutures in the bladders and chromic catgut in the ureters. Three months postoperatively in bladders sutured with polyglactin 910 small epithelial cysts were noted, which increased in size with time. In ureters sutured with polyglactin 910 cystic diverticula were observed eight months postoperatively. Because of the difference of tissue reaction to polyglactin 910 compared with catgut, further long-term studies are urged in different species of animals, prior to the clinical use of polyglactin 910 in the urinary tract.
豚鼠的膀胱切开术和犬的输尿管吻合术用聚乙醇酸910进行缝合。丝线和铬制肠线用作膀胱的对照缝线,输尿管则用铬制肠线。在用聚乙醇酸910缝合的膀胱中,术后三个月观察到小的上皮囊肿,其大小随时间增加。在用聚乙醇酸910缝合的输尿管中,术后八个月观察到囊性憩室。由于与肠线相比,组织对聚乙醇酸910的反应存在差异,因此在聚乙醇酸910临床用于泌尿道之前,迫切需要在不同种类的动物中进行进一步的长期研究。