Renwick D S, Connolly M J
Department of Geriatric Medicine, University of Manchester, UK.
Thorax. 1996 Feb;51(2):164-8. doi: 10.1136/thx.51.2.164.
Chronic airways obstruction is common in adults and the elderly. To investigate the possibility that older adults with obstructive airways disease frequently do not receive appropriate treatment, the respiratory symptoms, medication use, and pulmonary function were studied in a random sample of white adults aged over 45 living in central Manchester, UK.
A postal questionnaire survey was performed on 783 men and women aged 45 years and over selected from GP lists by random number tables. Subjects completing the questionnaire were invited to attend for pulmonary function testing and methacholine challenge (Newcastle dosimeter method).
The questionnaire response rate was 92.3% (723 subjects). The mean age of the population was 66.1 years and 57.2% were women; 29.2% were current smokers and 37.3% were ex-smokers. Asthma or bronchitis was reported by 30.0%. Two hundred and forty seven representative subjects attended for pulmonary function testing and spirometric evidence of chronic airways obstruction was found in 26.4%. Respiratory symptoms were reported by 76.6% of subjects with chronic airways obstruction; 55.0% had features which may predict potential improvement on treatment (increased non-specific bronchial responsiveness or significant bronchodilator reversibility). However, only 55.4% of subjects with airways obstruction had received a diagnosis of asthma or chronic bronchitis and only 36.9% were using inhaled bronchodilators or steroids.
Chronic airways obstruction is very common in adults in this inner city population, but is frequently overlooked. Most subjects with chronic airways obstruction are not receiving appropriate treatment.
慢性气道阻塞在成年人和老年人中很常见。为了调查患有阻塞性气道疾病的老年人经常得不到适当治疗的可能性,我们对居住在英国曼彻斯特市中心的45岁以上白人成年人的随机样本进行了呼吸症状、药物使用和肺功能的研究。
通过随机数表从全科医生名单中选取783名45岁及以上的男性和女性进行邮寄问卷调查。完成问卷的受试者被邀请参加肺功能测试和乙酰甲胆碱激发试验(纽卡斯尔剂量计法)。
问卷回复率为92.3%(723名受试者)。人群的平均年龄为66.1岁,57.2%为女性;29.2%为当前吸烟者,37.3%为既往吸烟者。30.0%的人报告患有哮喘或支气管炎。247名有代表性的受试者参加了肺功能测试,其中26.4%发现有慢性气道阻塞的肺量计证据。76.6%的慢性气道阻塞受试者报告有呼吸症状;55.0%的人具有可能预示治疗后潜在改善的特征(非特异性支气管反应性增加或显著的支气管扩张剂可逆性)。然而,只有55.4%的气道阻塞受试者被诊断为哮喘或慢性支气管炎,只有36.9%的人使用吸入性支气管扩张剂或类固醇。
在这个市中心人群中,慢性气道阻塞在成年人中非常常见,但经常被忽视。大多数慢性气道阻塞受试者没有得到适当的治疗。