Posyniak A, Semeniuk S, Zmudzki J, Niedzielska J, Biernacki B
Department of Pharmacology and Toxicology, National Veterinary Research Institute, Poland.
Vet Res Commun. 1996;20(2):167-74. doi: 10.1007/BF00385638.
Laying hens were dosed orally with dimetridazole (DMZ) (50 and 250 mg/kg) for 3 days or intramuscularly (50 mg/kg), also for 3 days, and the residues were determined by liquid chromatography in albumen and yolk. The sensitivity of the whole procedure was 2 ng/g. The drug was excreted preferentially into the yolk (about 57% of the total) and the elimination period lasted for 4-6 days after treatment.
给蛋鸡口服二甲硝唑（DMZ）（50毫克/千克和250毫克/千克），持续3天，或肌肉注射（50毫克/千克），同样持续3天，然后通过液相色谱法测定蛋白和蛋黄中的残留量。整个检测过程的灵敏度为2纳克/克。药物优先排泄到蛋黄中（约占总量的57%），治疗后消除期持续4 - 6天。
