Gracey M, Cullity G J
Arch Dis Child. 1977 Apr;52(4):325-7. doi: 10.1136/adc.52.4.325.
Basal gastric acid output was reduced in 9 out of 14 infants and young children with malnutrition compared with 21 age-matched controls. In all the patients the response of the gastric mucosa to stimulation by pentagastrin was impaired, and gastritis of variable severity was present in 8 out of the 9 patients in who biopsies were performed. Impaired gastric acid secretion probably contributes towards bacterial overgrowth and diarrhoeal diseases in malnourished children.
与21名年龄匹配的对照相比，14名营养不良的婴幼儿中有9名基础胃酸分泌减少。所有患者胃黏膜对五肽胃泌素刺激的反应均受损，在进行活检的9名患者中，有8名存在不同程度的胃炎。胃酸分泌受损可能是导致营养不良儿童细菌过度生长和腹泻疾病的原因之一。
