el-Sadr W, Medard F, Berthaud V
Division of Infectious Diseases, Harlem Hospital Center, New York, NY 10037, USA.
Am J Public Health. 1996 Aug;86(8):1146-9. doi: 10.2105/ajph.86.8_pt_1.1146.
A directly observed therapy program was established at Harlem Hospital, New York, NY, in 1993 to promote high tuberculosis treatment completion rates.
The Harlem program used an on-site surrogate family model. Treatment completion rate, visit adherence rate, human immuno-deficiency virus seroprevalence, and time to sputum culture conversion were assessed.
Out of 145 enrolled patients with suspected and confirmed tuberculosis, 95 (92 confirmed and 3 suspected) continued treatment. The visit adherence rate was 91.1 +/- 7.9%, with one patient (1%) lost to follow-up.
High rates of treatment completion and visit adherence were achieved because of unique program characteristics. Thus, directly observed therapy is advocated as a means of ensuring treatment completion.
1993年在纽约州纽约市的哈莱姆医院设立了一个直接督导治疗项目,以提高结核病的高治疗完成率。
哈莱姆项目采用了现场替代家庭模式。评估了治疗完成率、就诊依从率、人类免疫缺陷病毒血清流行率以及痰培养转阴时间。
在145名登记的疑似和确诊结核病患者中,95名(92名确诊和3名疑似)继续接受治疗。就诊依从率为91.1 +/- 7.9%,有一名患者(1%)失访。
由于该项目的独特特点,实现了高治疗完成率和就诊依从率。因此,提倡直接督导治疗作为确保治疗完成的一种手段。