Huffnagle H J, Norris M C, Leighton B L, Arkoosh V A
Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Anesth Analg. 1996 Jan;82(1):8-12. doi: 10.1097/00000539-199601000-00003.
Preoperative local anesthetic blockade of somatosensory pathways involved with skin incision and other noxious perioperative stimuli may "preempt" or attenuate the postoperative pain response. Since the Pfannenstiel incision lies within the L1 dermatome, bilateral ilioinguinal, iliohypogastric nerve blocks (IINBs) should provide analgesia after low transverse cesarean section. We designed this study to compare the analgesic effect of IINBs placed before or after cesarean delivery. Forty-six patients undergoing cesarean delivery with spinal anesthesia were enrolled. Patients were randomly assigned to one of three groups: Before, After, or None. Bilateral IINBs were placed with 0.5% bupivacaine, 10 mL to each side. Twenty-two patients had IINBs placed before surgery (11 failed blocks), 12 had blocks placed after surgery, and 12 had no block. Morphine, through a patient-controlled analgesia (PCA) pump, provided additional postoperative analgesia. A blinded observer assessed 24-h morphine use as well as patient satisfaction and pain scores ("incisional" and "overall") for 96 h. Although there were no consistent differences in pain scores among the groups, patients in the After group occasionally reported more pain than those in the Before and None groups. Patient satisfaction and morphine use did not differ among the groups. We conclude that there is no benefit to ilioinguinal nerve blocks, either before or after surgery, in patients who receive spinal anesthesia for elective cesarean delivery. Our finding of increased pain in the After group is perplexing and requires confirmation.
术前对与皮肤切口及其他围手术期有害刺激相关的体感通路进行局部麻醉阻滞,可能会“抢先”或减轻术后疼痛反应。由于耻骨联合上横切口位于L1皮节范围内,双侧髂腹股沟、髂腹下神经阻滞(IINB)应能在低位横切口剖宫产术后提供镇痛效果。我们设计了本研究,以比较剖宫产分娩前或后进行IINB的镇痛效果。纳入了46例行脊髓麻醉下剖宫产分娩的患者。患者被随机分为三组之一:术前组、术后组或无阻滞组。双侧IINB均采用0.5%布比卡因,每侧10 mL。22例患者在手术前进行IINB(11例阻滞失败),12例在手术后进行阻滞,12例未进行阻滞。吗啡通过患者自控镇痛(PCA)泵提供额外的术后镇痛。一名盲法观察者评估了24小时吗啡用量以及患者96小时的满意度和疼痛评分(“切口”和“总体”)。尽管各组之间疼痛评分没有一致差异,但术后组患者偶尔报告的疼痛比术前组和无阻滞组患者更多。各组之间患者满意度和吗啡用量没有差异。我们得出结论,对于接受脊髓麻醉进行择期剖宫产分娩的患者,术前或术后进行髂腹股沟神经阻滞均无益处。我们在术后组发现疼痛增加这一结果令人困惑,需要进一步证实。