日本名古屋的两例原藻病病例。

Two cases of protothecosis in Nagoya, Japan.

作者信息

Matsumoto Y, Shibata M, Adachi A, Ohashi M, Kanbe T, Tanaka K

机构信息

Department of Dermatology, Nagoya University School of Medicine, Japan.

出版信息

Australas J Dermatol. 1996 May;37 Suppl 1:S42-3. doi: 10.1111/j.1440-0960.1996.tb01082.x.

DOI:10.1111/j.1440-0960.1996.tb01082.x

PMID:8713014

Abstract

Two cases of protothecosis caused by Prototheca wickerhamii have been reported from Nagoya in a 12 year period in both cases the infection presented on the cheeks of otherwise healthy women. Biopsies showed numerous PAS positive staining organisms with the distinctive mulberry like endosporulation in the dermis. Prototheca wickerhamii was identified on sugar assimilation tests of colonies isolated from tissue on Sabouraud agar. Case 1 responded to 11 months of oral ketoconazole therapy. Case 2 might not respond to itraconazole. The source of the infections has not been identified.

摘要

在12年期间，名古屋报告了2例由威克汉姆原藻引起的原藻病。在这两个病例中，感染均出现在原本健康的女性脸颊上。活检显示真皮中有大量PAS阳性染色的生物体，具有独特的桑葚样内生孢子形成。通过对从沙氏琼脂培养基上的组织分离出的菌落进行糖同化试验，鉴定出威克汉姆原藻。病例1对口服酮康唑治疗11个月有反应。病例2可能对伊曲康唑无反应。感染源尚未确定。