Boshnakova Ts, Georgiev A, Strashimirov D
Department of Pathological Anatomy, Higher Medical School, Sofia.
Eksp Med Morfol. 1994;32(1-2):32-40.
The authors examined the liver of 20 rabbits "Newzeland white" and "Chinchila", undergone atherogenic diet with cholesterol (0.3-0.5 g/kg body weight) for 30 and 60 days. They determined cholesterol, lipids, triglicerides and beta-lipoproteins in the serum. The morphologic study revealed accumulation of cholesterol in the hepatocytes, fibrosis, proliferation of the bile ducts and signs of hepatic cirrhosis.
作者检查了20只“新西兰白兔”和“青紫蓝兔”的肝脏，这些兔子接受了含胆固醇（0.3 - 0.5克/千克体重）的致动脉粥样化饮食，持续30天和60天。他们测定了血清中的胆固醇、脂质、甘油三酯和β-脂蛋白。形态学研究显示肝细胞中胆固醇积累、纤维化、胆管增生以及肝硬化迹象。
