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[对久效磷中毒所致心肌损害的纠正]

[The correction of post-poisoning damages to the myocardium caused by carbophos].

作者信息

Myshkin V A, Bakhtizina G Z, Bashkatov S A, Varlamova T I, Volkova E S, Enikeev D A

出版信息

Anesteziol Reanimatol. 1995 Nov-Dec(6):54, 56-7.

PMID:8713423
Abstract

Lipid peroxidation processes and levels of oxidative metabolism enzymes succinate and lactate dehydrogenases, as well as morphometric parameters of cardiomyocytes were studied in rats after exposure to malathion. The efficacy of oxymethacil and atropin correction of postintoxication injuries to the myocardium was assessed. The new drug oxymethacil is recommended to be included in the treatment protocols during the first 48 h after grave poisoning with malathion.

摘要

研究了马拉硫磷染毒大鼠的脂质过氧化过程、氧化代谢酶琥珀酸脱氢酶和乳酸脱氢酶的水平,以及心肌细胞的形态计量学参数。评估了甲氧嘧啶和阿托品对中毒后心肌损伤的纠正效果。建议在马拉硫磷重度中毒后的最初48小时内,将新药甲氧嘧啶纳入治疗方案。

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