Makarov G F, Budagov R S, Moiseeva L A, Boldueva N G
Medical Research Radiological Centre, Russian Academy of Medical Sciences, Obninsk.
Antibiot Khimioter. 1995 Aug;40(8):36-9.
The efficacy of pefloxacin, a novel promising antibacterial drug of the group of fluoroquinolones, was studied on mice against doxycycline in the prevention and treatment of infectious complications of radiation/thermal injury. According to the data on the effect of the antibiotics on the resistance to exogenic infection and the development of dysbacteriosis pefloxacin was recommended for the use in the scheme of combined therapy of radiation/thermal injury.
对新型有前景的氟喹诺酮类抗菌药物培氟沙星在小鼠身上针对强力霉素预防和治疗辐射/热损伤感染性并发症的疗效进行了研究。根据抗生素对外源性感染抵抗力及菌群失调发展影响的数据，推荐培氟沙星用于辐射/热损伤联合治疗方案。
