Hübner W A, Plas E G, Pflüger H, Hauck M, Miko I, Furka I
Department of Urology, Lainz Hospital, Vienna, Austria.
Neurourol Urodyn. 1996;15(2):149-55. doi: 10.1002/(SICI)1520-6777(1996)15:2<149::AID-NAU4>3.0.CO;2-F.
Five female mongrel dogs were used in an acute animal experiment. Under general anesthesia two monopolar wire electrodes armed with needles on either side were implanted into the bladder wall, the leads of both electrodes were then pulled through the abdominal wall. Filling of the bladder and intravesical pressure measurement were achieved through a suprapublic percutaneous cystostomy. Electrostimulation was carried out using the XEJ-2 experimental electroejaculator (biphasic pulses, pulse width 2.5 msec, approximately 70 mAmp, 50 Hz). The pressure changes within the bladder following electrostimulation were recorded, the effect of stimulation was observed endoscopically. Electrostimulation of the bladder wall resulted in micturition in all cases, showing an initial pressure peak at the commencement of electrostimulation followed by a decrease after onset of evacuation. We believe that laparoscopic implantation of temporary wire electrodes followed by percutaneous electrostimulation may open up new possibilities for bladder rehabilitation as well as for diagnostic investigations into the contractile capabilities of the bladder.
在一项急性动物实验中使用了5只雌性杂种犬。在全身麻醉下，将两侧带有针头的两个单极线状电极植入膀胱壁，然后将两个电极的导线经腹壁引出。通过耻骨上经皮膀胱造瘘实现膀胱充盈和膀胱内压力测量。使用XEJ - 2型实验性电射精器进行电刺激（双相脉冲，脉冲宽度2.5毫秒，约70毫安，50赫兹）。记录电刺激后膀胱内的压力变化，通过内镜观察刺激效果。膀胱壁的电刺激在所有病例中均导致排尿，在电刺激开始时出现初始压力峰值，随后在排尿开始后下降。我们认为，腹腔镜植入临时线状电极后进行经皮电刺激可能为膀胱康复以及膀胱收缩能力的诊断研究开辟新的可能性。
