Bogye G, Tompos G
Országos Reumatológiai és Fizioterápiás Intézet III. Belgyógyászat.
Orv Hetil. 1996 Feb 11;137(6):287-90.
Following a short historical review the authors summarize the latest results regarding domestic iodine supply. Iodine content in drinking waters, samples of mother's milk, urine and goiter screening data from all regions of Hungary unanimously verify that significant part of the population is deficient in iodine, yet supplementation of iodine is still even today an unsolved problem in our country. In the search for the reasons the authors review the theoretical possibilities of iodine supplementation by discussing advantages and disadvantages of the individual models. They establish that alimentary iodine supplementation in itself is not suitable due to both theoretical and practical reasons for the complete elimination of iodine deficiency, therefore they make recommendations to supplement iodine in other ways. They also discuss the effect of selenium deficiency on the metabolism of thyroid hormones. They call attention that domestic, endemic selenium deficiency may be related to the frequency of Hungarian occurrences of iodine deficiency disorders. The authors review the iodine deficiency disorders and their effects on the health of present and future generations. They compare the practical benefit and costs of iodine supplementation, and furthermore discuss in detail the possible side effects of iodine supplementation.
在进行简短的历史回顾后，作者总结了国内碘供应的最新成果。匈牙利所有地区的饮用水、母乳样本、尿液中的碘含量以及甲状腺肿筛查数据一致证实，相当一部分人口存在碘缺乏问题，然而即便在今天，碘补充在我国仍是一个未解决的问题。为探寻原因，作者通过讨论各模型的优缺点来审视碘补充的理论可能性。他们认定，出于理论和实际原因，仅靠膳食补充碘本身并不足以完全消除碘缺乏，因此他们建议通过其他方式补充碘。他们还讨论了硒缺乏对甲状腺激素代谢的影响。他们提醒注意，国内地方性硒缺乏可能与匈牙利碘缺乏疾病的发病频率有关。作者回顾了碘缺乏疾病及其对当代和后代健康的影响。他们比较了碘补充的实际益处和成本，此外还详细讨论了碘补充可能产生的副作用。
