Arenas C, Gil-Peralta A, Otero A, Crespo P
Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla.
Rev Neurol. 1996 Feb;24(126):224-6.
We present the preliminary results of the effects on percutaneous translumenal angioplasty (PTA) cerebral haemodynamics in thirty patients with important stenosis of the internal carotidal artery.
Using transcranial doppler (TCD) with acetazolamide (ACZ) as a vasodilatory stimulus, we assessed vasomotor reactivity (VR and pulsatility index (Pl) both before and three months after angioplasty. We also carried out single photon emission computerized tomography (SPECT) and cartography and frequency measurement by electroencephalogram (EEG) again both before and after PTA.
Of the first twelve patients who completed the study, VR was maintained in nine and PI increased after PTA in seven. In three patients VR was exhausted and in two recovered after PTA.
PTA improved cerebral haemodynamics. Similar more exhaustive studies are needed if revascularization techniques are to be useful in treating patients with this level of stenosis but who are asymptomatic as to the risk of haemodynamic cerebral vasomotor angioplasty.
我们展示了对30例颈内动脉严重狭窄患者经皮腔内血管成形术（PTA）对脑血流动力学影响的初步结果。
使用经颅多普勒（TCD）并以乙酰唑胺（ACZ）作为血管舒张刺激剂，我们在血管成形术前和术后三个月评估了血管运动反应性（VR）和搏动指数（PI）。我们还在PTA前后再次进行了单光子发射计算机断层扫描（SPECT）以及脑电图（EEG）的图谱绘制和频率测量。
在完成研究的前12例患者中，9例患者的VR得以维持，7例患者在PTA后PI升高。3例患者的VR耗竭，2例患者在PTA后恢复。
PTA改善了脑血流动力学。如果血管重建技术要用于治疗具有这种狭窄程度但无血流动力学性脑血管运动血管成形术风险症状的患者，则需要进行类似的更详尽研究。
