Cox C, Marsh D, Myers G, Clarkson T
Department of Biostatistics, University of Rochester School of Medicine, New York 14642, USA.
Neurotoxicology. 1995 Winter;16(4):727-30.
In this paper we report additional results from the analysis of dose-response data on delayed development from the outbreak of methylmercury poisoning in rural Iraq during the winter of 1971-72. The discussion is focused on the importance of four influential points for the estimation of the population threshold for the effects of methylmercury. The point is made that while this study was important for establishing a dose-response relationship in humans, the uncertainty in the parameters of this relationship is large, and further human studies are needed.
在本文中，我们报告了对1971 - 1972年冬季伊拉克农村甲基汞中毒爆发后发育迟缓剂量反应数据进行分析得出的更多结果。讨论聚焦于四个有影响力的点对于估计甲基汞效应的人群阈值的重要性。指出尽管这项研究对于确立人类中的剂量反应关系很重要，但该关系参数的不确定性很大，还需要进一步的人体研究。
