Greenfield E, Jordan B
Crit Care Nurs Clin North Am. 1996 Jun;8(2):203-15.
The development of effective topical chemotherapy, the reintroduction of burn wound excision, and the use of biologic dressings have significantly decreased the incidence of invasive burn wound infection and have contributed to the improvement in the survival that has occurred over the past four decades. The currently available skin substitutes are imperfect, and research endeavors continue in the effort to develop a nonantigenic disease-free, readily available, physiologically effective tissue that will promptly effect wound closure, reduce scar formation and thereby improve cosmetic results, and reduce the need for reconstructive surgery. As monitoring and physiologic support techniques improve and additional advances in wound care occur, the morbidity and mortality of burn patients will be further reduced.
有效的局部化疗的发展、烧伤创面切除的重新引入以及生物敷料的使用，显著降低了侵袭性烧伤创面感染的发生率，并促进了过去四十年来生存率的提高。目前可用的皮肤替代物并不完美，研究工作仍在继续，旨在开发一种无抗原、无疾病、易于获得、生理上有效的组织，这种组织将迅速实现伤口闭合，减少疤痕形成，从而改善美容效果，并减少重建手术的需求。随着监测和生理支持技术的改进以及伤口护理的进一步进展，烧伤患者的发病率和死亡率将进一步降低。
