Lemli J
Termeredellelaan, Winksele Belgique.
Bull Acad Natl Med. 1995 Nov;179(8):1605-11.
A review of the recent progress in the study of the mode of action of the sennosides, the active constituents of the senna drug, is presented. An interaction between rhein anthrone, the active metabolite of the sennosides, and the immune cells of the colon is suggested as a base for laxative activity.
本文综述了番泻叶药物活性成分番泻苷作用模式研究的最新进展。有人提出，番泻苷的活性代谢产物大黄酸蒽酮与结肠免疫细胞之间的相互作用是泻药活性的基础。
