6-羟基多巴胺对鸡对半抗原二硝基苯基抗体反应的影响。
Effects of 6-Hydroxydopamine on the antibody response to the hapten dinitrophenyl in the chicken.
作者信息
Yasuda M, Furusawa S, Satoh A, Taura Y, Nakama S, Yoshihara K, Hirota Y
机构信息
Laboratory of Immune Cytology, National Institute of Animal Health, Ibaraki, Japan.
出版信息
J Vet Med Sci. 1995 Dec;57(6):1073-5. doi: 10.1292/jvms.57.1073.
Antibody responses to the hapten dinitrophenyl (DNP) and the concentration of catecholamine in chickens received a single injection of 6-Hydroxydopamine (6-OHDA) into the chorioallantoic cavity at the embryonal stage were evaluated. A significantly enhanced anti-DNP IgA response and a markedly decreased level of noradrenaline in the peripheral blood were observed in chickens treated with 400 micrograms of 6-OHDA at 14 days of incubation. These results suggested the immunomodulatory influence of the sympathetic nervous system.
评估了胚胎期在鸡胚绒毛尿囊腔单次注射6-羟基多巴胺（6-OHDA）后，鸡对半抗原二硝基苯基（DNP）的抗体反应以及儿茶酚胺的浓度。在孵化14天时用400微克6-OHDA处理的鸡中，观察到抗DNP IgA反应显著增强，外周血中去甲肾上腺素水平明显降低。这些结果提示了交感神经系统的免疫调节作用。
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