通过A系小鼠肺部肿瘤反应检测美国饮用水中有机污染物的致癌性。
Test for carcinogenicity of organic contaminants of United States drinking waters by pulmonary tumor response in strain A mice.
作者信息
Theiss J C, Stoner G D, Shimkin M B, Weisburger E K
出版信息
Cancer Res. 1977 Aug;37(8 Pt 1):2717-20.
PMID:872098
Abstract
The production of lung adenomas in strain A following multiple i.p. injections of selected organic water contaminants was investigated. Of the 16 contaminants tested, only bromoform produced a pulmonary adenoma response that was significantly greater than the pulmonary adenoma response of vehicle-treated control mice.
摘要
研究了在A品系小鼠中多次腹腔注射选定的有机水污染物后肺腺瘤的产生情况。在测试的16种污染物中，只有溴仿产生的肺腺瘤反应明显大于用赋形剂处理的对照小鼠的肺腺瘤反应。
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