Wilbourn J, Montesano R
Environ Health Perspect. 1982 Nov;45:127-8. doi: 10.1289/ehp.8245127.
This paper presents a short review of the available carcinogenicity tests which have been carried out on various phthalate esters prior to the availability of the National Cancer Institute bioassay studies. All of these studies suffer from diverse limitations in design or reporting when compared to more recent experimental protocols and reports. There are three papers related to di(2-ethylhexyl) phthalate, one to di-n-butyl phthalate, two to butyl benzyl phthalate, one to ethyl phthalyl ethyl glycolate nd another to butyl phthalylbutyl glycolate (1).
本文简要回顾了在美国国立癌症研究所进行生物测定研究之前,针对各种邻苯二甲酸酯所开展的现有致癌性试验。与近期的实验方案和报告相比,所有这些研究在设计或报告方面都存在各种局限性。有三篇论文涉及邻苯二甲酸二(2-乙基己基)酯,一篇涉及邻苯二甲酸二正丁酯,两篇涉及邻苯二甲酸丁苄酯,一篇涉及邻苯二甲酰乙基乙醇酸乙酯,另一篇涉及邻苯二甲酰丁基丁二醇酯(1)。