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1988年至1991年阿尔巴尼亚地拉那婴幼儿轮状病毒肠胃炎毒株的电泳图谱

Electropherotypes of rotavirus strains causing gastroenteritis in infants and young children in Tirana, Albania, from 1988 to 1991.

作者信息

Superti F, Diamanti E, Giovannangeli S, Dobi V, Xhelili L, Donelli G

机构信息

Department of Ultrastructures, Istituto Superiore di Sanitá, Rome, Italy.

出版信息

Acta Virol. 1995 Dec;39(5-6):257-61.

PMID:8722294
Abstract

During 1988-1991, an epidemiological survey was conducted in Tirana (Albania) on group A rotavirus strains which cause gastroenteritis in infants and young children. Rotaviruses were detected in 312 of 1,241 (25.1%) examined specimens from children with acute diarrhoea. Viruses were detected throughout the study period. Among the 72 rotavirus strains tested for double-stranded RNA (dsRNA) electrophoretic migration pattern, 9 different electropherotypes were recognized, 1 of those being more frequent than the others. At the beginning and at the end of the examined period (1988 and 1990-1991) two different long electropherotypes were predominant, whereas in 1989 (middle period) short electropherotypes were common indicating an involvement of virus strains with short electropherotypes in hospitalization-requiring diarrhoeas occurring in the area surveyed in that year.

摘要

1988年至1991年期间,在地拉那(阿尔巴尼亚)针对导致婴幼儿肠胃炎的A组轮状病毒毒株开展了一项流行病学调查。在1241名患有急性腹泻儿童的检测样本中,有312份(25.1%)检测出轮状病毒。在整个研究期间均检测到了病毒。在对72株轮状病毒毒株进行双链RNA(dsRNA)电泳迁移模式检测时,识别出9种不同的电泳型,其中1种比其他类型更为常见。在调查期开始和结束时(1988年以及1990 - 1991年),两种不同的长电泳型占主导地位,而在1989年(中期),短电泳型较为常见,这表明短电泳型病毒毒株与当年调查地区发生的需要住院治疗的腹泻有关。

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