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Evaluation of the laboratory rabbit model for screening topical mosquito repellents.

作者信息

Rutledge L C, Gupta R K, Mehr Z A, Buescher M D, Reifenrath W G

机构信息

Department of Entomology, Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA.

出版信息

J Am Mosq Control Assoc. 1996 Mar;12(1):142-3.

PMID:8723273
Abstract

The laboratory rabbit was evaluated as a model for screening topical mosquito repellents, using data obtained in tests of deet (N,N-diethyl-3-methylbenzamide) against Aedes aegypti on humans and rabbits. Host-specific differences in the action of the test material were quantified by multiple regression analysis. The test material was less effective but more persistent in tests on rabbits, and responses of the mosquito test population were more variable.

摘要

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