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男性精神分裂症患者嗅觉皮质投射区域的代谢减退：一项正电子发射断层扫描初步研究

Hypometabolism in olfactory cortical projection areas of male patients with schizophrenia: an initial positron emission tomography study.

作者信息

Bertollo D N, Cowen M A, Levy A V

机构信息

Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.

出版信息

Psychiatry Res. 1996 Mar 29;60(2-3):113-6. doi: 10.1016/0165-1781(96)02619-4.

DOI:10.1016/0165-1781(96)02619-4
PMID:8723301
Abstract

Several studies have reported olfactory deficits in schizophrenic patients. This study examines local cerebral metabolic rate within two cortical areas in eight normal men and eight schizophrenic men. A significantly greater degree of hypometabolism was observed in the schizophrenic men in the cortical area of the nondominant hemisphere that receives direct uncrossed olfactory projections.

摘要

多项研究报告了精神分裂症患者存在嗅觉缺陷。本研究检测了8名正常男性和8名精神分裂症男性两个皮质区域内的局部脑代谢率。在接受直接非交叉嗅觉投射的非优势半球皮质区域，观察到精神分裂症男性的代谢减退程度明显更大。

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