Humphrey K R, Gruemer H D, Lott J A
Clin Chem. 1977 Jul;23(7):1343-6.
The impact of water shifts due to changes in posture has been reinvestigated for serum protein and calcium concentrations in a young, healthy population. We found that generaly accepted normal ranges for total serum protein, and to a lesser degree for total serum calcium, are not acceptable as a reference range for a hospitalized population that is predominantly in a supine position. Our data indicate a smaller biological variability for total protein and calcium for a reference population in the recumbent posture as compared to the same population in the upright position.
针对年轻健康人群，重新研究了因姿势改变导致的水分转移对血清蛋白和钙浓度的影响。我们发现，对于主要处于仰卧位的住院人群而言，普遍接受的总血清蛋白正常范围以及在较小程度上的总血清钙正常范围，都不能作为参考范围。我们的数据表明，与同一人群站立时相比，参考人群卧位时总蛋白和钙的生物学变异性更小。
