Hughes T A, Liu P, Griffiths H, Lawrie B W, Wiles C M
Department of Medicine (Neurology), University of Wales College of Medicine, Heath Park, Cardiff, UK.
Physiol Meas. 1996 May;17(2):109-19. doi: 10.1088/0967-3334/17/2/005.
Simultaneous videofluoroscopy and electrical impedance tomography (EIT) were performed in 13 patients. Subjects swallowed a low-conductivity and a higher-conductivity bolus of between 5 and 20 ml. EIT images from the two swallows were then subtracted to cancel out movement related changes. The peak in the conductivity change was most closely associated in time with a point at which the pharynx is filled with bolus: this suggests that the subtraction process does produce data and images which are related to the bolus rather than to movement of involved structures. The full width at 50% and 75% of the maximum of the time conductivity plot was correlated with the time taken for the bolus to be cleared from the mouth (r = 0.63 and 0.68 respectively, p < 0.05 for both). Despite the sampling frequency of only 9 frames s-1, compared to 50 frames s-1 for videofluoroscopy, EIT recordings from the neck are able to detect the presence of a conductive bolus in the pharynx and for the first time the relationship between parameters of an EIT time-conductivity plot and a measure of bolus transit using an accepted technique has been established.
对13名患者同时进行了视频荧光透视检查和电阻抗断层扫描（EIT）。受试者吞咽了5至20毫升的低电导率和高电导率团块。然后将两次吞咽的EIT图像相减，以消除与运动相关的变化。电导率变化的峰值在时间上与咽部充满团块的点最为密切相关：这表明相减过程确实产生了与团块相关而非与相关结构运动相关的数据和图像。时间电导率图最大值的50%和75%处的全宽与团块从口腔清除所需的时间相关（分别为r = 0.63和0.68，两者p < 0.05）。尽管采样频率仅为9帧/秒，而视频荧光透视检查为50帧/秒，但来自颈部的EIT记录能够检测到咽部导电团块的存在，并且首次建立了EIT时间电导率图参数与使用公认技术测量团块通过时间之间的关系。
