Graves M, Bergeman E R, Lawrence C B
Department of Cell Biology, Baylor College of Medicine, Houston TX 77030, USA.
Comput Biol Med. 1996 May;26(3):183-97. doi: 10.1016/0010-4825(95)00053-4.
We have developed a representation of genome data which has proven itself useful for describing data at a Human Genome Center. Genomic data have a graph-like structure and representing the concepts and relationships of genetics as a graph simplifies the development of databases for genome laboratories. Graphs are a comfortable communication medium for biologists and computer scientists and graph diagrams assist in the development of databases by facilitating the exchange of expertise. We have tailored a graph language for modeling genomic data and describe our process of using graphs to develop genome databases.
我们已经开发出一种基因组数据表示法，这种表示法已证明对描述人类基因组中心的数据很有用。基因组数据具有类似图的结构，将遗传学的概念和关系表示为图，简化了基因组实验室数据库的开发。图是生物学家和计算机科学家都能轻松使用的交流媒介，并且通过促进专业知识的交流，有助于数据库的开发。我们定制了一种用于对基因组数据进行建模的图语言，并描述了我们使用图来开发基因组数据库的过程。
