Reeh E S, Douglas W H, Levine M J
Minnesota Dental Research Center for Biomaterials and Biomechanics, Department of Oral Biology, School of Dentistry, University of Minnesota, Minneapolis, USA.
J Prosthet Dent. 1996 Jun;75(6):649-56. doi: 10.1016/s0022-3913(96)90251-6.
Mechanisms of salivary lubrication can be quantitatively measured by a reduction in the coefficient of friction. It is important that lubrication be assessed under the conditions of the oral cavity to properly assess lubrication regimes. The relative lubricity of three artificial salivas and two controls were assessed at a bovine enamel interface in an artificial mouth with a range of conditions that approximate oral function. Statistical analysis indicated that the enamel lubricity of sodium dodecylsulfate (SDS) and Oracare-D saliva substitutes were different from the other saliva substitutes and water. The low friction with Oracare-D and SDS saliva substitutes was because of resident amphipaths adsorbed at the enamel interface. Amphipaths adsorbed on enamel may provide a reduction in interocculsal friction and its resulting complications for patients with xerostomia.
唾液润滑机制可通过摩擦系数的降低进行定量测量。重要的是，应在口腔条件下评估润滑情况，以便正确评估润滑机制。在模拟口腔功能的一系列条件下，在人工口腔中的牛牙釉质界面评估了三种人工唾液和两种对照物的相对润滑性。统计分析表明，十二烷基硫酸钠（SDS）和Oracare-D唾液替代品的牙釉质润滑性与其他唾液替代品和水不同。Oracare-D和SDS唾液替代品的低摩擦是由于吸附在牙釉质界面的驻留两亲物。吸附在牙釉质上的两亲物可能会降低口干患者的咬合间摩擦及其引发的并发症。
