Romanovská L, Prerovsky I, Stríbrna J
Cor Vasa. 1977;19(1):61-5.
The maximal decrease of vascular resistance during reactive hyperaemia in lower limb was investigated in a group of healthy control persons, in hypertensives (stage II) with blood pressure level over 160/95 mmHg, in hypertensives (stage II) with pressure level below 160/95 mmHg, and in patients with atherosclerotic changes in the lower-limb arteries without signs of obliteration. Insufficient distensibility was found not only in hypertensives with pressure over 160/95 mmHg, but also in those with a normal pressure level at the time of examination (achieved by antihypertensive therapy or bed rest). A similar insufficient distensibility was observed in patients with atherosclerotic changes in the lower-limb arteries without obliteration. The findings support the view that anatomical rebuilding of vascular wall takes place in hypertension, and suggest that the incapacity of maximal dilatation is characteristic not only of resistance vessels but probably of larger arteries as well.
对一组健康对照者、血压水平超过160/95 mmHg的高血压患者（II期）、血压水平低于160/95 mmHg的高血压患者（II期）以及下肢动脉有动脉粥样硬化改变但无闭塞迹象的患者，研究了下肢反应性充血期间血管阻力的最大下降情况。结果发现，不仅血压超过160/95 mmHg的高血压患者存在扩张性不足，而且在检查时血压水平正常的患者（通过抗高血压治疗或卧床休息实现）中也存在这种情况。在下肢动脉有动脉粥样硬化改变但未闭塞的患者中也观察到类似的扩张性不足。这些发现支持了高血压时血管壁会发生解剖学重塑的观点，并表明最大扩张能力不足不仅是阻力血管的特征，可能也是较大动脉的特征。
