Hanevold C D, Lazarchick J, Constantin M A, Hiott K L, Orak J K
Department of Pediatrics, Medical College of Georgia, Augusta 30912, USA.
Ann Clin Lab Sci. 1996 May-Jun;26(3):279-82.
Plasma and urine concentrations of protein S were measured in five children with steroid-resistant nephrotic syndrome. It was found that plasma free protein S was reduced in three out of the five patients studied. Thus, acquired free protein S deficiency does occur in children with nephrotic syndrome and is one of many factors which may place them at risk for a thromboembolic event.
对五名激素抵抗型肾病综合征患儿测定了血浆和尿液中的蛋白S浓度。结果发现,在研究的五名患者中,有三名患者的血浆游离蛋白S降低。因此,肾病综合征患儿确实会出现获得性游离蛋白S缺乏,这是使他们面临血栓栓塞事件风险的众多因素之一。