Lin F M, Pan Y C, Hom C, Sabbahi M, Shenaq S
Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas, USA.
J Reconstr Microsurg. 1996 Apr;12(3):173-7. doi: 10.1055/s-2007-1006472.
This study attempted to develop a motor functional index, ankle stance angle (ASA), to assess rat sciatic nerve regeneration subsequent to autografting. ASA, 50 degrees in normal rats, is the ankle joint angle at the mid-stance phase of the gait cycle. In a nerve graft group, a 1-cm segment of the right sciatic nerve was transected and then repaired with nerve autograft. In an ungrafted group, the nerve gap was left unrepaired. ASA measured 4 months after surgery was statistically significantly larger in the nerve graft group (36 degrees) than in the ungrafted group (22 degrees). The results suggest that ASA is more sensitive than sciatic function index in detecting functional recovery after a complete sciatic nerve lesion. ASA also showed a significant correlation with the passive range of ankle joint motion and gastrocnemius muscle weight. The study concluded that ASA is a reliable index for assessment of regeneration of rat sciatic nerve after a complete lesion. The intra-rater reliability (r = 0.97 and 0.90) and inter-rater reliability (r = 0.85) tests performed support the conclusions.
本研究试图开发一种运动功能指标——踝关节站立角度（ASA），以评估大鼠自体移植后坐骨神经的再生情况。正常大鼠的ASA为50度，是步态周期中 stance 中期的踝关节角度。在神经移植组中，将右侧坐骨神经的1厘米节段切断，然后用自体神经移植进行修复。在未移植组中，神经间隙未进行修复。术后4个月测量的ASA在神经移植组（36度）中统计学上显著大于未移植组（22度）。结果表明，在检测完全性坐骨神经损伤后的功能恢复方面，ASA比坐骨神经功能指数更敏感。ASA还与踝关节被动活动范围和腓肠肌重量显著相关。该研究得出结论，ASA是评估大鼠完全性损伤后坐骨神经再生的可靠指标。所进行的组内可靠性（r = 0.97和0.90）和组间可靠性（r = 0.85）测试支持了这些结论。
