Howard M O, Cowley D S, Roy-Byrne P P, Hopfenbeck J R
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, USA.
Alcohol Clin Exp Res. 1996 May;20(3):445-8. doi: 10.1111/j.1530-0277.1996.tb01073.x.
Sons of alcoholics (SOAs; n = 27) and sons of nonalcoholics (SONAs; n = 23) were compared across Tridimensional Personality Questionnaire (TPQ) and Sensation Seeking scales and measures of plasma homovanillic acid and platelet monoamine oxidase activity. SOAs and SONAs did not differ significantly on any measure. The pattern of correlations between TPQ and Sensation Seeking scales provided some support for the construct validity of TPQ measures. Scores on the TPQ Novelty Seeking scale and platelet monoamine oxidase activity were significantly inversely associated (r = -0.52, p < 0.02) among SOAs, but not among SONAs (r = -0.06).
对酗酒者的儿子（SOA，n = 27）和非酗酒者的儿子（SONA，n = 23）进行了比较，比较内容包括三维人格问卷（TPQ）、感觉寻求量表以及血浆高香草酸和血小板单胺氧化酶活性的测量。在任何测量指标上，SOA和SONA之间均无显著差异。TPQ与感觉寻求量表之间的相关模式为TPQ测量的结构效度提供了一些支持。在SOA中，TPQ新奇寻求量表得分与血小板单胺氧化酶活性显著负相关（r = -0.52，p < 0.02），而在SONA中则不然（r = -0.06）。
