Ramdial P K, Nadvi S
Department of Anatomical Pathology, Faculty of Medicine, University of Natal, Congella, South Africa.
Neurosurgery. 1996 May;38(5):1040-3. doi: 10.1097/00006123-199605000-00037.
Although solitary fibrous tumors are well-recognized tumors, they have only recently been described in the orbit. Although histopathological awareness of the lesion has been heightened recently because of the discovery of CD-34 immunoreactivity in solitary fibrous tumors, including orbital lesions, it remains unrecognized clinically as a cause of unilateral proptosis. Clinical awareness of the lesion is important, because benign and malignant forms of the tumor occur. The malignant forms pursue an aggressive course manifested by local invasion, recurrent growth, or metastases. The benign lesions are histologically banal and are cured by surgical excision. This case report describes unilateral proptosis caused by an orbital solitary fibrous tumor, which occurred in a 43-year-old woman. The tumor had a benign histomorphology and clinical course, with surgical excision being curative. In reviewing the literature on orbital solitary fibrous tumors, clinical awareness of the tumor as a cause of unilateral proptosis is emphasized.
尽管孤立性纤维瘤是公认的肿瘤,但直到最近才在眼眶中被描述。由于在包括眼眶病变在内的孤立性纤维瘤中发现了CD-34免疫反应性,近年来对该病变的组织病理学认识有所提高,但临床上仍未将其视为单侧眼球突出的病因。对该病变的临床认识很重要,因为肿瘤有良性和恶性之分。恶性形式的肿瘤病程侵袭性强,表现为局部侵犯、复发或转移。良性病变在组织学上无明显特征,手术切除可治愈。本病例报告描述了一名43岁女性因眼眶孤立性纤维瘤导致的单侧眼球突出。该肿瘤具有良性的组织形态学和临床病程,手术切除可治愈。在回顾眼眶孤立性纤维瘤的文献时,强调了将该肿瘤视为单侧眼球突出病因的临床认识。