Kujas M, Poirier J
Service d'histologie-embryologie-cytogénétique, Groupe hospitalier Pitié-Salpêtrière, Paris.
Rev Prat. 1996 Feb 15;46(4):415-9.
Although the current radiological imaging is really performing, histologic examination remains essential in as much regarding the diagnosis as the pronostical assessment of cerebral tumors pronostic. The difficulties of histological diagnosis are not the same according to the various processes such as cerebral biopsy, extemporaneous examination or routine examination. Grading of gliomatous tumors is one among all the components that might enable pronostical assessment. Predictivity of meningiomas and pituitary adenomas recurrences remain unreliable despite numerous histological techniques that can be used (proliferative markers, bromodeoxyuridine incorporation, nucleolar organizers, flow cytometry).
尽管当前的放射影像学确实发挥着作用，但组织学检查对于脑肿瘤的诊断和预后评估仍然至关重要。根据诸如脑活检、即时检查或常规检查等不同过程，组织学诊断的难度各不相同。胶质瘤分级是所有可能有助于预后评估的因素之一。尽管有多种组织学技术（增殖标志物、溴脱氧尿苷掺入、核仁组织区、流式细胞术）可用于评估，但脑膜瘤和垂体腺瘤复发的预测性仍然不可靠。
