来自矮伞芹的三萜皂苷。次要脱酰基皂苷的结构。

Triterpenoid saponins from Bellium bellidioides. Structures of the minor deacylsaponins.

作者信息

Schöpke T, Wray V, Nimtz M, Hiller K

机构信息

Institut für Pharmazie, Humboldt-Universität zu Berlin, Germany.

出版信息

Phytochemistry. 1996 Mar;41(5):1399-403. doi: 10.1016/0031-9422(95)00791-1.

DOI:10.1016/0031-9422(95)00791-1

PMID:8729462

Abstract

A new deacylsaponin of polygalacic acid, desacylbellidioside B4, was obtained from the whole plants of Bellium bellidioides L. The structure has been elucidated by a general strategy involving mass spectrometry (ESI-MS, including tandem MS, and GC-MS) and high-field one- and two-dimensional NMR spectroscopy (1H and 13C NMR, COSY-45, HMQC, HMBC) as 3-O-alpha-L-rhamnopyranosyl-2 beta, 3 beta, 16 alpha, 23-tetrahydroxyolean-12-en-28-oic acid 28-O-alpha-L-rhamnopyranosyl(1-->3)-beta-D-xylopyranosyl(1-->4)-alpha-L- rhamnopyranosyl(1-->2)-[alpha-L-arabinofuranosyl(1-->3)-beta-D-fucopyran oside. Moreover, bellissaponin BS2 and besysaponin C12 have also been isolated, demonstrating the close chemical relationship of B. bellidioides to the Bellis genus.

摘要

从菊状小苦荬（Bellium bellidioides L.）的全草中获得了一种新的多聚半乳糖醛酸脱酰基皂苷——脱酰基苦荬皂苷B4。其结构已通过包括质谱法（电喷雾电离质谱，包括串联质谱和气相色谱 - 质谱）以及高场一维和二维核磁共振光谱法（氢谱和碳谱、COSY - 45、异核多量子相干谱、异核多键相关谱）的通用策略得以阐明，结构为3 - O - α - L - 鼠李吡喃糖基 - 2β，3β，16α，23 - 四羟基齐墩果 - 12 - 烯 - 28 - 酸28 - O - α - L - 鼠李吡喃糖基(1→3)-β - D - 木吡喃糖基(1→4)-α - L - 鼠李吡喃糖基(1→2)-[α - L - 阿拉伯呋喃糖基(1→3)-β - D - 岩藻吡喃糖苷。此外，还分离出了苦荬皂苷BS2和苦荬皂苷C12，这表明菊状小苦荬与雏菊属在化学上关系密切。