Saccardo F, Monti G, Rinaldi G, Pioltelli P, Mosconi L, Garelli G
Ia Division of Medicine, Saronno Hospital, Italy.
Clin Exp Rheumatol. 1995 Nov-Dec;13 Suppl 13:S165-6.
We investigated the presence of anti-GOR antibodies in patients with essential mixed cryoglobulinemia, since both autoimmune pathogenetic processes and a high prevalence of HCV infection are present in this syndrome.
We compared these cases to patients with HCV-related chronic active hepatitis or alcoholism, and to ex-blood donors. A total of 60 patients with biopsy-proven chronic liver disease were studied.
HCV related markers, cryoglobulins, anti-GOR antibodies and ANA were detected in all of the groups.
Our data would appear to indicate that anti-GOR are related to the presence of HCV chronic hepatitis and not to cryoglobulinemia or chronic liver damage.
