Petersen L K, Larsen E, Hansen A
Department of Gynecology and Obstetrics, University Hospital of Aarhus, Denmark.
Eur J Obstet Gynecol Reprod Biol. 1996 Apr;65(2):255-7. doi: 10.1016/0301-2115(95)02366-6.
Unmeasurable serum relaxin concentrations were found in repeated serum samples taken during two subsequent pregnancies in a woman pregnant after in vitro fertilization in artificial cycles. Despite the absence of relaxin both pregnancies were carried out normally until term except for symptoms of pelvic girdle relaxation. Labour induction was attempted at term as placental insufficiency was suspected. However, the cervical score remained unfavourable and Cesarian section was performed. In the second pregnancy elective Cesarian section was performed due to mild preeclampsia. This case indicates that relaxin may not be important for either suppression of myometrial activity or pelvic girdle relaxation during human pregnancy.
在人工周期体外受精后怀孕的一名妇女的两次连续妊娠期间采集的重复血清样本中,发现血清松弛素浓度无法测量。尽管缺乏松弛素,但两次妊娠均正常进行至足月,只是有骨盆带松弛的症状。由于怀疑有胎盘功能不全,足月时尝试引产。然而,宫颈评分仍然不理想,于是进行了剖宫产。在第二次妊娠中,由于轻度先兆子痫进行了择期剖宫产。该病例表明,松弛素可能对人类妊娠期间抑制子宫肌层活动或骨盆带松弛并不重要。