Fan X, Hynynen K
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Phys Med Biol. 1996 Apr;41(4):591-608. doi: 10.1088/0031-9155/41/4/002.
The spherically curved square element phased array design for ultrasound surgery was studied in several of its important aspects. A method for determining the spatial limitations of the multiple-foci region was developed for spherically curved phased arrays. The effects on the ultrasound fields of varying the phases and the amplitudes at control points were investigated. It was found that the phases and the magnitudes of control points have an impact on the ultrasound field distributions. The effects of multiple-foci spacing, pulse duration, and maximum temperature on the size and shape of necrosed tissue were investigated. For a spherically curved phased array with an 8 cm radius of curvature, an 8.8 x 8.8 cm2 projected area, and a 1.5 MHz operating frequency, the minimum number of phased array elements that could produce the largest acceptable necrosed tissue volume was 256. The tissue volume necrosed during the sonication could be increased to approximately 1 x 1 x 3 cm3 with this array.
对用于超声手术的球面弯曲方形单元相控阵设计的几个重要方面进行了研究。针对球面弯曲相控阵，开发了一种确定多焦点区域空间限制的方法。研究了控制点处相位和幅度变化对超声场的影响。发现控制点的相位和幅度对超声场分布有影响。研究了多焦点间距、脉冲持续时间和最高温度对坏死组织大小和形状的影响。对于曲率半径为8 cm、投影面积为8.8×8.8 cm²且工作频率为1.5 MHz的球面弯曲相控阵，能够产生最大可接受坏死组织体积的相控阵单元的最小数量为256。使用该阵列，超声处理期间坏死的组织体积可增加到约1×1×3 cm³。
