Ungersböck A, Pohler O E, Perren S M
Department of Orthopaedic Surgery, University of Bern, Switzerland.
Biomaterials. 1996 Apr;17(8):797-806. doi: 10.1016/0142-9612(96)81417-7.
Five types of limited contact dynamic compression plates (LC-DCPs) of pure titanium with different surface treatments and an electropolished stainless steel LC-DCP were tested. The surface roughness parameters and chemical surface conditions were determined and checked for probable surface contamination. After an implantation period of 3 months on long bones of sheep, the soft tissue adjacent to the plates was evaluated histomorphometrically. The difference in roughness parameters was statistically significant for most surface conditions. A correlation was found between the surface roughness of the implants and the thickness of the adjacent soft tissue layer. The thinnest soft tissue reaction layer with a good adhesion to the implant surface was observed for the titanium anodized plates with coarse surface. Smooth implants, in particular the electropolished stainless steel plates, induced statistically significant thicker soft tissue layers. Profilometer roughness measurements combined with scanning electron microscopy techniques were useful methods to characterize the surface morphology.
对五种经过不同表面处理的纯钛有限接触动力加压接骨板（LC-DCP）以及一块电解抛光不锈钢LC-DCP进行了测试。测定了表面粗糙度参数和化学表面状况，并检查是否存在可能的表面污染。在绵羊长骨上植入3个月后，对接骨板附近的软组织进行了组织形态计量学评估。对于大多数表面状况，粗糙度参数的差异具有统计学意义。发现植入物的表面粗糙度与相邻软组织层的厚度之间存在相关性。对于表面粗糙的阳极氧化钛接骨板，观察到与植入物表面具有良好附着力的最薄软组织反应层。表面光滑的植入物，特别是电解抛光不锈钢接骨板，会引起统计学上显著更厚的软组织层。轮廓仪粗糙度测量结合扫描电子显微镜技术是表征表面形态的有用方法。
