Hoshino K
Departamento de Fisiologia, Universidade Estadual Paulista, Botucatu, Brasil.
Braz J Med Biol Res. 1996 Jan;29(1):41-6.
Reports of the effect of desynchronized sleep (DS) deprivation on body temperature (Tb) of rats in the literature are contradictory. Since conspicuous body weight loss is common in such deprivation, the effect of food plus DS deprivation on Tb of adult male Wistar rats was studied. DS deprivation carried out by the small platform method with food ad libitum (N = 8) induced hyperthermia (Tb above 38.5 degrees C) in 1 to 3 rats daily until the 8th day, when a case of discrete hypothermia (Tb below 36.9 degrees C) appeared. Food deprivation alone started to induce hypothermia on the third day in one (20%) out of five rats. Fasting imposed from the 5th to the 8th day of DS deprivation (N = 12) caused hypothermia in 33% and 67% of the animals on the second and third day of starvation, respectively. DS compensatory manifestations in 6 starved rats intensified (N = 2) or precipitated (N = 2) hypothermia after the end of sleep deprivation. It is concluded that the hypothermia is not a primary effect of DS deprivation, and this state of sleep seems to have its particular functional role which is independent of thermoregulation.
文献中关于不同步睡眠（DS）剥夺对大鼠体温（Tb）影响的报道相互矛盾。由于在这种剥夺过程中明显的体重减轻很常见，因此研究了食物加DS剥夺对成年雄性Wistar大鼠Tb的影响。采用小平台法在自由进食情况下进行DS剥夺（N = 8），每天有1至3只大鼠出现体温过高（Tb高于38.5摄氏度），直至第8天，此时出现一例体温离散性过低（Tb低于36.9摄氏度）的情况。仅食物剥夺在五只大鼠中的一只（20%）于第三天开始引起体温过低。在DS剥夺的第5至8天实施禁食（N = 12），分别在饥饿的第二天和第三天导致33%和67%的动物出现体温过低。6只饥饿大鼠在睡眠剥夺结束后的DS代偿表现加剧（N = 2）或引发（N = 2）了体温过低。得出的结论是，体温过低不是DS剥夺的主要效应，这种睡眠状态似乎具有其独立于体温调节的特定功能作用。
